FLOR-COLIS powder
COMPOSITION:
Each gm contains:
Florfenicol……………………………..100 mg
Neomycin Sulphate…………………..150 mg
Oxytetracycline HCl (BP)……….300 mg (As per innovator specification)
DESCRIPTION:
NEOMYCIN is a broad-spectrum bactericidal aminoglycosidic antibiotic with particular activity against certain members of the Enterobacteriaceae e.g. Escherichia coli. Its mode of action is at the ribosomal level. Neomycin is not inactivated by enzymes or food. These pharmacological properties lead to neomycin being an efficacious antibiotic in the prevention and treatment of enteric infections caused by bacteria sensitive to neomycin.
FLORFENICOL is a synthetic broad-spectrum antibiotic that is effective against most Gram-positive and Gram-negative bacteria isolated from domestic animals. Florfenicol, a fluorinated derivative of chloramphenicol, acts by inhibiting protein synthesis at the ribosomal level and is bacteriostatic. Florfenicol does not carry the risk of inducing human aplastic anaemia that is associated with the use of chloramphenicol, and also has activity against some chloramphenicol-resistant strains of bacteria.
OXYTETRACYCLINE belongs to the group of tetracyclines and acts bacteriostatic against many Gram-positive and Gram-negative bacteria like Bordetella, Bacillus, Corynebacterium, Campylobacter, E. coli, Haemophilus, Pasteurella, Salmonella, Staphylococcus and Streptococcus spp. and Mycoplasma, Rickettsia and Chlamydia spp. The mode of action of oxytetracycline is based on inhibition of bacterial protein synthesis. Oxytetracycline is mainly excreted in urine. (Note: trailing text cut off slightly at the edge of the line).
INDICATION:
FLOR-COLIS Gastrointestinal and respiratory infections caused by oxytetracycline, Neomycin & Florfenicol sensitive bacteria like Bordetella, Bacillus, Corynebacterium, Campylobacter, E. coli, Haemophilus, Pasteurella, Salmonella, Staphylococcus and Streptococcus spp. and Mycoplasma, Rickettsia and Chlamydia spp. in Calves, goats & poultry.
DOSAGE:
For oral administration:
Calves, goats and sheep: Twice daily 1 g per 50 – 100 kg body weight for 3 – 5 days.
Poultry: 1g per 2 – 4 litres of drinking water for 3 – 5 days.
WITHDRAWAL TIMES:
For meat: Calves, goats, sheep: 21 days. Poultry: 7 days.
PRECAUTIONS / احتیاط:
Always store at room temperature, (avoid extreme temperature). / ہمیشہ کمرے کے درجہ حرارت پر ذخیرہ کریں۔
Protect from direct sunlight and moisture. / سورج کی روشنی اور نمی سے بچائیں۔
Keep out of reach of children and animals. / بچوں اور جانوروں کی پہنچ سے دور رکھیں۔
After each use close container securely. / استعمال کے بعد بوتل کو محفوظ طریقے سے بند کریں۔
Wash hands thoroughly after use. / ہاتھوں کو اچھی طرح دھو لیں۔
